The main responsibility as a Scientist is to guarantee the correct design and execution of experiments for the development and validation of immunological assays to be used in the analysis of samples from clinical trials. The activities must be executed, documented and reported according to ...
CLS Services is a leading professional recruitment agency, specialised in the recruitment and career coaching of people with a background in chemistry & life sciences. For our client, Janssen Vaccines & Prevention, we are searching for a Scientist Clinical Immunology.
Janssen Vaccines & Prevention is dedicated to bringing meaningful innovation to global health. They focus on the discovery, development, manufacturing and marketing of vaccines and antibodies to protect people world-wide from infectious diseases.
The Clinical Immunology department is responsible for the immunological evaluation of vaccine candidates in clinical trials. In close collaboration with the Biomarker group and clinical development group, the clinical immunology department executes the immuno strategies and ensures the development, and validation of the required immunological assays as well as clinical sample analysis and data reporting. Typical assays to determine the immunogenicity of vaccines are the antibody ELISA, T cell ELISpot, Intracellular Cytokine Staining, and virus neutralization assays. The clinical immunology department offers Janssen Vaccines with services in Scientific and operational excellence, with high standards of quality and compliance.
The main responsibility as a Scientist is to guarantee the correct design and execution of experiments for the development and validation of immunological assays to be used in the analysis of samples from clinical trials. The activities must be executed, documented and reported according to Good Clinical Laboratory Practice (GCLP) quality requirements.
Other responsibilities are:
- Performing experiments on a regular basis to support assay development processes, but also to maintain your technical edge, and to remain aware of the issues and potential areas of improvement in the laboratory;
- Instructing associate and assistant scientist on the scientific fundamentals of the assays which are used in the lab, and to review to the data generated by them;
- The scientific quality of the analysis of clinical trial samples, as well as long term life cycle of the methods;
- Consider the long-term strategies of the project and align your scientific strategy accordingly.
Who we're looking for
The ideal candidate has a PhD in biological/medical sciences with a strong immunology or virology background. You have at least 2-3 years experience within a (bio)pharmaceutical company.
You have extensive, hands-on experience in the development and validation of serology (ELISA, Virus Neutralization Assays etc.) or cell-based assays (ELISPOT, Flow cytometry etc.) according to regulatory standards. You have experience with experimental plans using the “Design of Experiment (DoE)” principles. Recent experience in optimizing serology or cell-based assays and working with PBMCs is an advantage. Also knowledge and/or affinitiy with biostatistics and data analysis will be considerd as a plus.
Additionally, you have experience in working under quality standards such as GCLP, GCP or GMP.
On a personal level, you have good communication skills in English, you are quality minded and you are able to motivate and empower others.
Are you the experienced team player we are looking for?
Additional vacancy information
Contract: Temporary contract with CLS Services
Terms: Full time preferred, 32 hours discussable.
Contactperson: Claudia Erwich-Faaij
Phone: +31 (0)88 22 77 555
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