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Associate Scientist Biochemistry & Antigenicity

2019-04-15 LabResource | Leiden | HBO | Tijdelijk / Projectbasis | Sluit 2019-06-14

The Bacterial Vaccine department is seeking a talented Associate Scientist to join the Biochemical assays and Antigenicity Screening group. The successful candidate will be part of a dynamic and highly motivated team driving the characterization/ and evaluation of large molecule entities that are b

Janssen Vaccines & Prevention is a leading biotechnology company developing vaccines against infectious diseases. LabResource has been elected as their top supplier for the second year in a row and has been contracted to recruit for this position.



Job Description

The Bacterial Vaccine department is seeking a talented Associate Scientist to join the Biochemical assays and Antigenicity Screening group. The successful candidate will be part of a dynamic and highly motivated team driving the characterization/ and evaluation of large molecule entities that are being developed in different vaccine programmes. During your work, you will interact with various Bacterial Vaccines teams, and with Janssen Vaccine support departments. You will be expected to perform laboratory work in person and help contract research organizations (CROs) plan and execute their assignments. This position has therefore a strong focus on biochemical and immunological expertise. Resonosibilities include:

• Chemical modification of bacterial surface molecules;

  • Analysis of antigen-antibody interactions;
  • Analyze carbohydrate, protein-, or glycoconjugate-based antigens;
  • Know, implement and improve established tests for carbohydrates, proteins, glycoconjugates, and particle-based vaccines;
  • Develop new biochemical methods (evaluate LoD, LoQ, accuracy, etc.);
  • With help from product development specialists, design and implement biochemical assays for in-process control (IPC), product characterization, and product release;
  • Support CROs to plan, execute, document, and review their work;


Job Requirements

For this position we are recruiting laboratory professional with the following background:

  • Bachelor or Master degree (BSc / MSc) in a relevant discipline such as (micro) biology, life sciences, biochemistry;
  • 2-4 years of professional experience (industry experience is a must);
  • Expert knowledge on various biochemical assays (large molecules): HPLC, colorimetric assays, ELISA, Cell based assays, labelling of biomolecules;
  • Experience with SPR / Biolayer interferometry / Mesoscale thermophoresis / ITC based screening of biochemical interactions is advantageous;
  • Very good knowledge on bacterial cell surface molecules;
  • Experience and knowledge on chemical modification of microbial surface components;
  • Significant knowledge on purification and enrichment of large biochemical entities;
  • You are a problemsolver with a pragmatic hands-on approach;
  • You are a flexible team player who can work well assertively & independently;
  • Valid work permit is a must, PhD is overqualified and will not be taken into consideration.



Salary and Benefits

Contract: 1 year, via LabResource, realistic long term perspectives

Salary: ranging from €2800 - €3400 gross monthly

Hours:full time

Holidays: 25+12

Region: Leiden



Contact Us
Interesse, klik op de solliciteerknop om direct te solliciteren. Ook kun je telefonisch contact opnemen met LabResource via T.: 020 - 406 9750 of een CV per e-mail toesturen naar tremijn@labresource.nl.



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